Conditions/Hereditary Cancers/Chapter
Genetic Counseling
Consent, results, and family communication
Germline testing has medical, psychological, and family implications. Counseling exists before and after the test — reading a raw report alone is not enough, especially when variants of uncertain significance (VUS) appear.
Key points
- Before testingTap for details
Clarify the question, possible result categories (pathogenic / negative / VUS), costs, and how relatives might be informed.
- After testingTap for details
Pathogenic findings guide screening, risk-reducing options, and cascade testing. A negative result does not always erase clinical risk based on family history.
- PrivacyTap for details · key note inside
Genetic results are sensitive health data. Use planned secure transfer rather than informal file dumps.
- ImportantTap for details · key note inside
This page is for education. It is not medical advice and does not replace a visit with your physician.
Frequently asked questions
- What is a VUS?Tap for details
A variant of uncertain significance — it needs expert interpretation and is not treated as a proven pathogenic finding.
- Should I send raw genetic PDFs on WhatsApp?Tap for details
Prefer secure clinical channels. Avoid sharing ID numbers or unnecessary personal data in chat apps.
More chapters in this hub
Hereditary Cancer Overview
When hereditary risk is considered and how sequencing works
Lynch Syndrome
MMR/MSI, colorectal risk, and family screening
BRCA and Familial Breast Risk
Who is offered testing; surgery and surveillance frame
FAP
Polyposis, APC, and surgical timing
CDH1
Hereditary diffuse gastric cancer risk
Li-Fraumeni Syndrome
TP53 and multi-cancer spectrum
Peutz–Jeghers Syndrome
Hamartomatous polyps and surveillance
Molecular Testing in Cancer
Organ-specific biomarkers that often open this conversation
Appointment / info
This page is for education. It is not medical advice and does not replace a visit with your physician.
Medical editor: Assoc. Prof. Cengiz Dibekoğlu, MD · Last medically reviewed: August 2026 · English patient-education chapter.