Written and medically reviewed by: Assoc. Prof. Cengiz Dibekoğlu, MD, General SurgeryLast updated:
FAP (Familial Adenomatous Polyposis)
APC, heavy polyp burden, and surgical timing
Classic FAP is linked to germline APC changes and can produce hundreds to thousands of colorectal adenomas. Without planned care, colorectal cancer risk is very high. The path usually combines endoscopy, family history, and genetic counseling. It differs from Lynch mainly by polyp burden and gene pathway.
Outcomes of any surgical or interventional procedure may vary from person to person. Please seek a detailed consultation with your physician before any procedure.
© Cengiz Dibekoğlu — illustrative; not for unauthorized use
Figure summary
This educational figure shows: FAP.
Key points
When to consider FAP
Young-onset numerous colon polyps, family polyposis/colectomy history, or selected extracolonic clues (for example desmoid disease or duodenal polyps) open evaluation.
- Key note inside
Surgical frame
Risk-reducing colectomy timing and reconstruction options are planned with genetics, gastroenterology, and surgery together.
Family and follow-up
Pathogenic APC findings trigger cascade testing and structured endoscopic/surgical surveillance, including selected extracolonic risks.
- Key note inside
Important
This page is for education. It is not medical advice and does not replace a visit with your physician.
Frequently asked questions
Is every multi-polyp colon FAP?
No. Attenuated FAP and MUTYH-associated polyposis (MAP) are discussed separately.
Is colectomy mandatory at diagnosis?
Timing and extent are individualized by polyp load, rectum status, and goals — not one package for everyone.
More chapters in this hub
Hereditary Cancer Overview
When hereditary risk is considered and how sequencing works
Lynch Syndrome
MMR/MSI, colorectal risk, and family screening
BRCA and Familial Breast Risk
Who is offered testing; surgery and surveillance frame
MUTYH and Serrated Polyposis
MAP, serrated pathway, and surveillance intervals
CDH1
Hereditary diffuse gastric cancer risk
Li-Fraumeni Syndrome
TP53 and multi-cancer spectrum
Peutz–Jeghers Syndrome
Hamartomatous polyps and surveillance
Genetic Counseling
Consent, results, and talking with relatives
Molecular Testing in Cancer
Organ-specific biomarkers that often open this conversation
Appointment / info
This page is for education. It is not medical advice and does not replace a visit with your physician.
Medical editor: Assoc. Prof. Cengiz Dibekoğlu, MD · Last medically reviewed: August 2026 · English patient-education chapter.