Lynch Syndrome

• Why MMR/MSI is checked+−

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  Universal MMR/MSI assessment in new colorectal cancers informs immunotherapy discussions, prognosis framing, and Lynch evaluation — it is not reserved only for young patients.

• Surgery and follow-up+−

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  Resection extent and surveillance intensity depend on confirmed risk, anatomy, and patient goals. There is no single package for every Lynch patient.

• Family cascade+−

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  Pathogenic germline findings trigger relative testing and screening conversations under genetic counseling.

• Important+−

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  This page is for education. It is not medical advice and does not replace a visit with your physician.

More chapters in this hub

• Hereditary Cancer Overview

  When hereditary risk is considered and how sequencing works

• BRCA and Familial Breast Risk

  Who is offered testing; surgery and surveillance frame

• FAP

  Polyposis, APC, and surgical timing

• CDH1

  Hereditary diffuse gastric cancer risk

• Li-Fraumeni Syndrome

  TP53 and multi-cancer spectrum

• Peutz–Jeghers Syndrome

  Hamartomatous polyps and surveillance

• Genetic Counseling

  Consent, results, and talking with relatives

• Molecular Testing in Cancer

  Organ-specific biomarkers that often open this conversation