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Assoc. Prof. Cengiz Dibekoğlu, MD

General Surgeon · Laparoscopic · Robotic · Oncologic Surgery

Oncology landmark studies

Scientific Studies Atlas

This hub gathers selected landmark clinical studies that shaped cancer treatment, organized by disease category. Patient-friendly summaries and the gold-star (paradigm-changing) classification are editorially approved; numeric study cards are kept in each disease atlas. Survival and follow-up times use the median, not the mean.

176 unique landmark records

Treatment-changing discoveries · 47

Gold-star studies: 47. This count covers the main oncology atlas together with approved breast and thyroid studies. The main oncology subset has 39 stars.

  • Scientific accuracy — links to primary publications
  • Comparative atlas — no implied superiority
  • Clinical position — stage and endpoints kept separate
  • Patient language — complex results in plain terms
Upper digestive tract anatomy — landmark atlas entry illustration

Counts shown come live from the registry; example numbers in design drafts are not data.

Endpoints such as DFS, OS, pCR, and cCR are not interchangeable. Gold stars are never assigned automatically. No study cards are generated for empty categories. A patient summary is not a treatment recommendation.

A. Landmark studies

Important studies that changed cancer treatment with strong clinical evidence · 47 gold stars (main oncology 39 + breast/thyroid)

B. Emerging Research in Surgical Oncology

Promising, ongoing, or awaiting-results clinical research (no gold stars)

Discoveries That Changed Cancer TreatmentColonRectumGastricPancreasEsophagus / GEJBreastMelanomaLiver (HCC)Peritoneal / HIPECGISTNETThyroidBiliary

Discovery collection

Discoveries That Changed Cancer Treatment

How patients were treated before, what the research showed, and what changed today — read 47 gold-star discoveries without needing to know the study name. This count covers the main oncology atlas together with approved breast and thyroid studies (main oncology subset: 39). Includes “per 100 patients” figures and “what did it not prove?” fields.

Open the discovery hub

176 unique landmark records (main oncology + breast + thyroid; de-duplicated by atlas anchor) · counts are live

Disease categories

Active cards open the matching disease atlas. Study counts are calculated from the registry; draft example counts are not data.

Featured studies

Only studies that have a real card on this site are listed.

Central study index

176 records. Full numeric cards are on each atlas page; no placeholder results for empty categories.

Evidence-based medicine

Results are linked to primary publications and DOIs.

Comparative atlas

No indirect superiority claims across different stages or designs.

Current clinical position

Endpoints (OS/DFS/PFS) are never used interchangeably.

Patient-friendly explanation

Every card has a separate patient-message field.

Conclusion

Every study was designed for a specific patient group, treatment arm, and primary endpoint. Results should not be automatically generalized to other diseases or to all patients.

Evidence

Scientific sources

Show sources · 3

Oncology landmark studies hub: routes to disease-specific atlas pages. Numeric cards stay on disease atlases; empty categories show no fabricated results.

  1. Management of Locally Advanced Rectal Cancer: ASCO GuidelineAmerican Society of Clinical Oncology (ASCO) · 2024 · DOI: 10.1200/JCO.24.01160Open source
  2. Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-upESMO · 2017 (see the ESMO GI portal for updates) · DOI: 10.1093/annonc/mdx224Open source
  3. NCCN Clinical Practice Guidelines in Oncology: Rectal CancerNCCN · Current versionOpen source

Source list last checked: 31 October 2026. (Page content review date may appear separately above.)

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